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Posted: July 01, 2008

Small Electronic Device May Zap Away Migraines Before They Start

There's not much worse than a migraine headache, but now there may be a quick and easy way to get rid of one. Researchers say a novel portable electronic device designed may be able to "zap" away migraine pain before it starts.


Results of the study, presented at the annual American Headache Society meeting in Boston, found that the experimental device is safe and effective in eliminating headaches when administered during the onset of a migraine.

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With one in eight Americans suffering from chronic migraines, Dr. Yousef Mohammad, a neurologist and principal investigator of the study at Ohio State University's Medical Center, says the study results are promising given that only 50% to 60% of migraine patients respond to traditional migraine drug treatments.


The noninvasive transcranial magnetic stimulator (TMS) device interrupts the aura phase of the migraine, often described as electrical storms in the brain, before they lead to headaches. Migraine sufferers often describe "seeing" showers of shooting stars, zigzagging lines and flashing lights, and experiencing loss of vision, weakness, tingling or confusion, followed by intense throbbing head pain, nausea and vomiting.


Previous studies conducted at Ohio State used a heavy and bulky TMS device that reduced headache pain. To expedite treatment at home, a portable hand-held device was developed and tested.


"Stimulation with magnetic pulses from the portable TMS device proved effective for the migraine patients," said Mohammad. "Because of the lack of adverse events in this trial and the established safety of the TMS device, this is a promising treatment for migraines with aura. This sets the stage for future studies in migraines without aura."


The TMS device sends a strong electrical current through a metal coil, which creates an intense magnetic field for about one millisecond. This magnetic pulse, when held against a person's head, creates an electric current in the neurons of the brain, interrupting the aura before it results in a throbbing headache.


"The device's pulses are painless and safe," Mohammad said. "Since almost all migraine drugs have some side effects, and patients are prone to addiction from narcotics, or developing headaches from frequent use of over-the-counter medication, the TMS device holds great promise for migraine sufferers."


Of the 164 patients involved in Ohio State’s multi-center, randomized clinical trial receiving TMS treatment, 39% were pain free at the two-hour post-treatment point, compared to 22% in the group receiving "sham" pulses. There were no differences reported related to adverse reactions between the two groups.


(Article courtesy of

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